Gene description for HSPA1A
Gene name	heat shock protein family A (Hsp70) member 1A
Gene symbol	HSPA1A
Other names/aliases	HSP70 HSP70-1 HSP70-2 HSPA1 HSPA1B HSPA2
Species	Bos taurus
Experiment description of studies that identified HSPA1A in Bovine milk
1 Experiment ID 1045 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 12 h and 24 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
2 Experiment ID 1046 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 72 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
3 Experiment ID 1047 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 48 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
4 Experiment ID 1048 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - mature milk Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
5 Experiment ID 1163 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 12000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
6 Experiment ID 1164 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 35000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
7 Experiment ID 1165 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 70000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
8 Experiment ID 1166 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 100000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
9 Experiment ID 2815 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Western blotting Mass spectrometry Small RNA sequencing EV-TRACK -
10 Experiment ID 2822 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Mass spectrometry Small RNA sequencing EV-TRACK -